Early postoperative anesthetic complications after gastrectomy in patients with gastric cancer

Authors

DOI:

https://doi.org/10.24866/3033-5485/2025-3/93-100

Keywords:

gastric cancer, gastric resection, anesthetic complications, combined anesthesia, pain syndrome, stress hormones, postoperative period

Abstract

Gastric resection remains the primary radical treatment for gastric cancer, but the early postoperative period is often complicated by anesthetic-related adverse events. The influence of different anesthesia techniques on the incidence of these complications, as well as the role of clinical and organizational factors, remains insufficiently studied. In this regard, the purpose of the work – to assess the structure, frequency, and risk factors of early anesthetic complications in patients undergoing gastrectomy for gastric cancer, with a focus on the method of anesthesia. The study showed that сombined anesthesia with an epidural component provides more stable early postoperative outcomes and reduces the incidence of complications and stress responses. These findings have practical value for optimizing anesthetic protocols in upper abdominal oncological surgery. 

Author Biographies

  • Shakhnoza T. Iskandarova, Tashkent Pediatric Medical Institute

    Doctor of Medical Sciences, Professor, Head of the Department of Public Health and Healthcare Management

  • Anvar S. Yusupov, Tashkent Pediatric Medical Institute

    Doctor of Medical Sciences, Аssociate Professor of the Department of Anesthesiology and Resuscitation

  • Laylo N. Khakimova, Tashkent Pediatric Medical Institute

    Basic Doctoral Student of the Department of Public Health and Healthcare Management

References

Сунь Х., Неред С., Трякин А., Бугаев В., Строганова А., Кузнецова О., Чжун Б., Имаралиев О., Стилиди И. Прогностическая значимость микросателлитной нестабильности у больных раком желудка, получающих неоадъювантную терапию // Вопросы онкологии. 2023. Т. 69, № 2. С. 275–284. https://doi.org/10.37469/0507-3758-2023-69-2-275-284 = Sun H., Nered S., Tryakin A., Bugaev V., Stroganova A., Kuznetsova O., Zhong B., Imaraliev O., Stilidi I. Prognostic value of microsatellite instability in gastric cancer patients receiving neoadjuvant therapy. Oncology Issues, 2023, vol. 69, no. 2, pp. 275–284. (In Russ.). https://doi.org/10.37469/0507-3758-2023-69-2-275-284

Rosa F., Alfieri S. Laparoscopic gastrectomy for locally advanced gastric cancer. JAMA Surgery, 2022, vol. 157, no. 6, pp. 545–546. https://doi.org/10.1001/jamasurg.2021.7582

Hirano Y., Konishi T., Kaneko H., Itoh H., Matsuda S., Kawakubo H., Uda K., Matsui H., Fushimi K., Daiko H., Itano O., Yasunaga H., Kitagawa Y. Early postoperative non-steroidal anti-inflammatory drugs and anastomotic leakage after oesophagectomy. British Journal of Surgery, 2023, vol. 110, no. 2, pp. 260–266. https://doi.org/10.1093/bjs/znac399

Александрова Е.А., Хороненко В.Э., Маланова А.С., Захаренкова Ю.С., Суворин П.А. Оценка кардиопротективных свойств лидокаина как адъювантного компонента общей анестезии при онкоторакальных вмешательствах // Анестезиология и реаниматология. 2023. № 1. С. 39–48. https://doi.org/10.17116/anaesthesiology202301139 = Aleksandrova E.A., Khoronenko V.E., Malanova A.S., Zakharenkova Yu.S., Suvorin P.A. Evaluation of cardioprotective properties of lidocaine as an adjuvant in general anesthesia during thoracic oncological surgery. Anesthesiology and Resuscitation, 2023, no. 1, pp. 39–48. (In Russ.). https://doi.org/10.17116/anaesthesiology202301139

Deana C., Vetrugno L., Bignami E., Bassi F. Peri-operative approach to esophagectomy: a narrative review from the anesthesiological standpoint. Journal of Thoracic Disease, 2021, vol. 13, no. 10, pp. 6037–6051. https://doi.org/10.21037/jtd-21-940

He H., Ma Y., Zheng Z., Deng X., Zhu J., Wang Y. Early versus delayed oral feeding after gastrectomy for gastric cancer: A systematic review and meta-analysis. International Journal of Nursing Studies, 2022, vol. 126, article 104120. https://doi.org/10.1016/j.ijnurstu.2021.104120

Аллахвердян А.С., Анипченко А.Н., Анипченко Н.Н., Тульских Д.А. Непосредственные результаты лапароскопических резекций желудка и гастрэктомий при раке // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и технические науки. 2021. № 7. С. 153–156. DOI: https://doi.org/10.37882/2223-2966.2021.07.03 = Allahverdyan A.S., Anipchenko A.N., Anipchenko N.N., Tulskikh D.A. Immediate outcomes of laparoscopic gastric resections and gastrectomies in cancer. Modern Science: Current Problems of Theory and Practice. Series: Natural and Technical Sciences, 2021, no. 7, pp. 153–156. (In Russ.). https://doi.org/10.37882/2223-2966.2021.07.03

Седаков И.Е. и др. Симптоматические оперативные вмешательства при осложнённых формах рака желудка // Новообразование. 2021. Т. 13, № 1. С. 23–29. https://doi.org/10.26435/neoplasm.v13i1.350 = Sedakov I.E., et al. Symptomatic surgeries for complicated forms of gastric cancer. Neoplasm, 2021, vol. 13, no. 1, pp. 23–29. (In Russ.). https://doi.org/10.26435/neoplasm.v13i1.350

Недбайло И.Н. Сравнительный анализ влияния нейроаксиального блока и комбинированной анестезии на показатели физического статуса и лабораторные параметры в раннем послеоперационном периоде // Современные проблемы науки и образования. 2020. № 5. https://doi.org/10.17513/spno.30157 = Nedbailo I.N. Comparative analysis of neuraxial block and combined anesthesia effects on physical and laboratory parameters in early postoperative period. Modern Problems of Science and Education, 2020, no. 5. (In Russ.). https://doi.org/10.17513/spno.30157

Лейдерман И.Н., Медведев А.Ю., Еремеева О.Г., Зуков Р.А. Проблемы ранней диагностики и коррекции белково-энергетической недостаточности у пациентов высокого операционно-анестезиологического риска в абдоминальной онкохирургии: обзор литературы // Вестник интенсивной терапии имени А.И. Салтанова. 2024. № 3. С. 96–113. https://doi.org/10.21320/1818-474X-2024-3-96-113 = Leiderman I.N., Medvedev A.Yu., Eremeeva O.G., Zukov R.A. Early diagnosis and correction of protein-energy deficiency in high-risk oncological patients: a literature review. Bulletin of Intensive Therapy named after A.I. Saltanov, 2024, no. 3, pp. 96–113. (In Russ.). https://doi.org/10.21320/1818-474X-2024-3-96-113

Шаров С.В. Обоснование организационных мероприятий по совершенствованию онкологической помощи населению: автореф. дис. … канд. мед. наук. Санкт-Петербург, 2010. 22 с. = Sharov S.V. Substantiation of organizational measures to improve oncological care: Abstract of Ph. D. (Med.) thesis. St. Petersburg, 2010. 22 p. (In Russ.).

Downloads

Published

2025-09-26

Issue

Section

АНЕСТЕЗИОЛОГИИЯ И РЕАНИМАТОЛОГИЯ

How to Cite

Early postoperative anesthetic complications after gastrectomy in patients with gastric cancer. (2025). Clinical and Fundamental Medicine, 1(3), 93-100. https://doi.org/10.24866/3033-5485/2025-3/93-100