Factor analysis of the prevalence of congenital malformations in children of Primorsky Krai
Keywords:
factor analysis, congenital anomalies, developmental defects, congenital malformations, risk factors, hygiene of children and adolescents, childhood disabilities, prevention, public health, genetic counselingAbstract
Both in Russia and abroad, congenital malformations in children remain a socially significant problem and do not lose relevance. In the Primorsky Krai and in Russia as a whole, the structure of congenital malformations in children is dominated by congenital malformations of the circulatory system, which is one of the main causes of mortality in our country. It is all the more important to conduct a comprehensive hygienic assessment of risk factors for the development of these pathologies and identify the most significant ones at the present time. The purpose of the study is to conduct a factor analysis of the most common causes of congenital malformation in children of the Primorsky Territory. Methods. For factor analysis, a computer program was used, the patent «Implementation of a multidimensional method for studying the relationships between variables based on a factor model in the case of the assumption of redundancy of this data». Results and conclusions. When constructing a correlation matrix, a strong positive relationship was found between environmental factors and the incidence of congenital malformation in children of Primorye (m = 0,19), as a result of which we can conclude that in the current model, the incidence of congenital malformation in children of Primorye is 50,4% dependent on factors environment and the remaining 49,6% are accounted for by other factors (social and medical). As a result of factor analysis, two main factors were established: 1 factor has a strong positive correlation with the incidence of children with congenital malformations and environmental factors, and 2 factor has a strong positive correlation with population income (social factor) and a strong negative correlation with the health of pregnant women (medical factor).
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