Combination of prophylactic subcutaneous mastectomy in a woman with a BRCA-1 gene mutation and subsequent pregnancy. Forensic medical aspect of the problem

Authors

Keywords:

breast cancer, BRCA-1 mutation, preventive mastectomy, residual glandular tissue, pregnancy, lactation, court proceedings

Abstract

Risk-reducing mastectomy with BRCA-1, 2 gene mutation should be considered with the patient as part of a multidisciplinary team, which should include both an oncologist surgeon and a gynecologist oncologist, whose task is to explain the risks associated with ovarian preservation. With subcutaneous mastectomy with the preservation of the nipple-areolar complex, glandular tissue is preserved, which can cause lactation at the onset of pregnancy. These issues should be explained to patients, otherwise lawsuits against clinics and doctors who performed risk-reducing mastectomy are not excluded.

Author Biographies

  • Olga А. Dmitrieva, Primorsky Regional Bureau of Forensic Medical Examination

    Doctor of Medical Sciences, Head of the Department of Complex Examinations

  • Vladimir I. Apanasevich, Pacific State Medical University

    Doctor of Medical Sciences, Professor of the Department of Oncology and Radiation Therapy

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Published

2025-02-20

Issue

Section

ONCOLOGY, RADIATION THERAPY

How to Cite

Combination of prophylactic subcutaneous mastectomy in a woman with a BRCA-1 gene mutation and subsequent pregnancy. Forensic medical aspect of the problem. (2025). Clinical and Fundamental Medicine, 1(1), 38-44. https://journals.dvfu.ru/clinfundmed/article/view/1488

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